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Some people tolerate tirzepatide better than semaglutide, while others experience the opposite
When treating PCOS with metabolic therapies , patients often experience a paradoxical reaction
In patients with T2DM, insulin concentrations are often already supranormal, and treatment with exogenous insulin does not appear to increase protein synthesis, reduce muscle protein breakdown or improve mitochondrial function [170,171,172]
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Lu H-C, Mackie K
The takeaway: even at the maximum dose, most side effects are uncomfortable but not dangerous when you arrive at that dose through proper titration
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